Corsi di studio in
Farmacia - Chimica e tecnologia farmaceutiche

Tuition will furnish a detailed description of the components of the animal cell structure which determine cell functioning. Tuition will also furnish the basic principle of the physiology of cell excitability.

 

Acquisition of the basic notions of cell biology. Understanding of the vital functions
for the survival of the tissue to which it belongs thanks to its molecular components.
Preparation for the basic concepts of General Physiology (2 year).

Prokaryote and eukaryote cells.
Cell components: H2O, ions, molecules and macromolecules. Enzymes and their function. Proteins: the polypeptide chain, protein folding and structure.
The cell membrane: the double lipid layer and integral proteins. Active and passive membrane transports. Simple diffusion, carriers, ion channels. Transport across epitheliums. Exocytosis and endocytosis.
Electrochemical equilibriums. Membrane potential. Nernst law. Resting membrane potential. Action potential generation and propagation. Receptors and signal transduction.
Cell respiration and mitochondria. Structure and function of mitochondria. Synthesis of ATP.
Components and function of cytoskeleton. Nucleus, DNA and chromosomes. Genes: function and structure. Replication, repair and recombination of the DNA. Transcription and protein syntesis. RNA polymerase and the production of the RNA messenger. RNA maturation. Post-translational modifications. Protein degradation. Gene expression regulation. Cellular differentiation. Regulators of transcription: repressors and inducers. Mechanisms of cellular division. Cell cycle and its control: G1, S, G2 and M phases . CdK and their role in the control of the cell cycle.