- Oggetto:
In vivo PET Imaging, Drug Research and Development, Translational Research and Applications
- Oggetto:
In vivo PET Imaging, Drug Research and Development, Translational Research and Applications
- Oggetto:
Anno accademico 2019/2020
- Codice dell'attività didattica
- STF0271
- Corso di studi
- [f003-c504] laurea magistrale in chimica e tecnologia farmaceutiche - a torino
- Anno
- 4° anno
- Tipologia
- A scelta dello studente
- Crediti/Valenza
- 2
- SSD dell'attività didattica
- CHIM/08 - chimica farmaceutica
- Modalità di erogazione
- Tradizionale
- Lingua di insegnamento
- Inglese
- Modalità di frequenza
- Obbligatoria
- Tipologia d'esame
- Scritto ed orale
- Oggetto:
Sommario insegnamento
- Oggetto:
Obiettivi formativi
The aim of this course is to provide an outline of the basic principles and methods of PET, and an understanding of the basic physics, engineering and instrumentation underlying PET imaging; the basic principles of the design of PET tracers and the translation from preclinical to clinical studies, and how PET data are analyzed. This course will emphasize the strengths, usefulness and application of PET, so that any medicinal chemist engaging in a new research program can judge if, and how, his/her project could potentially benefit from this technology. The knowledge gained from this course will be valuable to any medicinal chemists, particularly those working in the pharmaceutical industry or in hospitals, or those involved in clinical trials, or who have access to medical imaging data, such as PET or PET/MR.
- Oggetto:
Programma
BASIC PRINCIPLES OF POSITRON EMISSION TOMOGRAPHY (PET)
PET is a non-invasive medical imaging technology that uses radiopharmaceuticals to trace in vivo
physiology and pharmacology. This course will provide an introduction to the fundamentals of PET and introduce some advanced topics. It will cover basic principles of the design of PET tracers, their use in drug research and development (R&D), and their applications in translation research from preclinical studies in animals to clinical investigation of biochemical transformations and drug mechanisms in humans.
Topics will be included:
Molecular Imaging: What can it do?
PET Radiotracer Development and Validation,
PET Studies of Drug Pharmacokinetics & Pharmacodynamics,
Preclinical PET,
State-of-the-art GMP Radiochemistry,
PET Translational Research,
PET Clinical Applications in Humans.
Testi consigliati e bibliografia
- Oggetto:
